Endocrine Abstracts

Infertility is a growing concern in Western countries. Several factors, including lifestyle habits and increased prevalence of chronic disorders associated with hormonal alterations, increased chronic inflammation and systemic oxidative stress (such as obesity and diabetes mellitus), are contributing to the reduction of reproductive potential among males in modern societies. Evidence suggests these factors negatively impact human sperm quality resulting in a combination of alt...

Infertility is a global health problem that affects about 15% of couples and approximately half of infertility cases are associated with male factors. Oxidative Stress (OS) is reported as one of the major causes of male infertility, mainly due to spermatozoa’s vulnerability to the attack of reactive oxygen species (ROS). Infertile couples often recur to assisted reproductive technology (ART) to achieve a successful pregnancy. However, ART protocols also increase the expos...